A Cotton Rat Model of Human Parainfluenza 3 Laryngotracheitis: Virus Growth, Pathology, and Therapy
نویسندگان
چکیده
منابع مشابه
Protection of cotton rats against human parainfluenza virus type 3 by vaccination with a chimeric FHN subunit glycoprotein.
A cotton rat model of experimental human parainfluenza virus type 3 (PIV-3) infection was used to examine the efficacy of FHN, a novel chimeric glycoprotein which contains the extracellular regions of the fusion (F) and haemagglutinin-neuraminidase (HN) glycoproteins of PIV-3. The FHN protein was expressed in insect cells using a baculovirus vector system. FHN vaccination resulted in induction ...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2002
ISSN: 0022-1899,1537-6613
DOI: 10.1086/345834